Ribosomal protein L36 pseudogene 10 (RPL36P10)

Ribosomal protein L36 pseudogene 10 (RPL36P10) is a processed pseudogene derived from the ribosomal protein L36 gene family.[5][6] Pseudogenes like RPL36P10 arise due to events such as gene duplication or retrotransposition but typically lack the ability to encode functional proteins due to mutations or absence of regulatory elements. As with most ribosomal protein pseudogenes, RPL36P10 is not transcribed into a functional protein, nor is there evidence it has a biological role or is involved in disease. It is not considered a therapeutic target, and no drugs are known to interact with this locus.[5][6] RPL36P10 is distinct from the functional RPL36 gene, which encodes a protein component of the 60S ribosomal subunit important for translation.[1][2] Processed pseudogenes such as RPL36P10 are widespread in the human genome, resulting largely from the retrotransposition of mRNA from protein-coding genes.[3] The presence of many ribosomal protein pseudogenes can complicate gene expression analyses and bioinformatics due to sequence similarity, but these pseudogenes themselves have no known physiological or pathological activity.[3] RPL36P10, as a pseudogene, does not encode a protein, does not participate in biological pathways, does not serve as a disease target or biomarker, and has no known functional or pathological impact in humans. It is included in various gene databases for genome annotation, but it is not relevant to therapeutic targeting or drug discovery.[5][6]

Other names

RPL36_3_697RPL36P10[6][5]