Ribosomal protein L36a pseudogene 11 (RPL36AP11)

Ribosomal protein L36a pseudogene 11 (RPL36AP11) is a processed pseudogene in the human genome that is related in sequence to the functional ribosomal protein L36a gene (RPL36A). The RPL36AP11 locus does not encode a functional protein and is categorized as a pseudogene, not a protein-coding gene, enzyme, receptor, or other canonical drug target. Like many ribosomal protein genes, clusters of related pseudogenes, including RPL36AP11, are scattered throughout the genome and have no known biological function, disease relevance, or role as therapeutic targets[7]. Key context: - RPL36AP11 differs fundamentally from its functional paralogs RPL36A and RPL36AL, both of which encode ribosomal proteins involved in protein synthesis and with reported links to diseases such as Diamond-Blackfan anemia and certain cancers[1][2][3][5]. - Pseudogenes like RPL36AP11 lack coding potential; some can regulate gene expression but there is no evidence this is the case for RPL36AP11 specifically. - RPL36AP11 is thus not considered a therapeutic target, biomarker, enzyme, or functional biological entity[7]. Summary: RPL36AP11 is a nonfunctional processed pseudogene with no confirmed protein product, biological role, disease implication, or utility as a drug target. Its designation as a gene "target" is likely incorrect for scientific and therapeutic purposes[7].

Other names

RPL36A_2_73RPL36AP11