Ribosomal protein L36a pseudogene 18 (RPL36AP18)

Ribosomal protein L36a pseudogene 18 (RPL36AP18) is a processed pseudogene in the human genome[10]. It shares high sequence similarity with the protein-coding gene ribosomal protein L36a (RPL36A), which encodes a structural component of the 60S ribosomal subunit[3][7][10]. However, RPL36AP18 does not encode a functional protein[10]. Like many pseudogenes, it is unlikely to possess significant biological or therapeutic relevance. It is not considered a drug target, nor does it participate in known cellular pathways, molecular functions, or disease processes[10]. Key context: - Pseudogenes such as RPL36AP18 arise from gene duplication or retrotransposition events involving functional genes (here, RPL36A), but they typically accumulate mutations rendering them nonfunctional[3][10]. - While some pseudogenes may exert regulatory roles at the RNA level in rare cases, there is no evidence that RPL36AP18 is functional or relevant in molecular pharmacology or therapeutics[10]. This entry should *not* be treated as a valid therapeutic target in drug discovery or biomedical research contexts.

Other names

RPL36A_5_491RPL36AP18