Target intelligence / Profile preview

Ribosomal protein L36a pseudogene 31 (RPL36AP31)

Target
RPL36AP31
Molecular classification
Processed pseudogene
01

Overview

Ribosomal protein L36a pseudogene 31 (RPL36AP31) is a processed pseudogene in the human genome that is related by sequence to the protein-coding gene RPL36A, which encodes a structural component of the 60S large subunit of the ribosome. Processed pseudogenes such as RPL36AP31 typically lack the ability to encode functional proteins and are considered "noncoding". While some pseudogenes have regulatory roles in modulating the expression of protein-coding genes (e.g., by acting as decoys for microRNAs or sources of siRNAs), specific functions for RPL36AP31 have not been described in the literature. No disease associations, drug interactions, or biomarker uses have been reported for this pseudogene.

Other names
RPL36A_13_923
02

Mechanism of action

None (not a druggable target; for general pseudogene function, possible regulatory roles by acting as miRNA decoys or sources of regulatory RNAs have been reported for select pseudogenes, but not specifically for RPL36AP31)

03

Biological functions

Pseudogenes generally do not encode functional proteins but can regulate the expression of parental genes or interact through noncoding RNA mechanisms in select cases
04

Disease associations

No specific disease role is described for RPL36AP31; however, some pseudogenes in general can be involved in gene regulation in diseases such as cancer

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