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Ribosomal protein L36a pseudogene 40 (RPL36AP40) is a pseudogene in Homo sapiens, named for its sequence similarity to the functional ribosomal protein L36a gene (RPL36A). Unlike the active RPL36A, this pseudogene does not encode a functional ribosomal protein and lacks experimental evidence of translation. Pseudogenes, such as RPL36AP40, can arise when gene copies accumulate mutations that disable their protein-coding capacity; some may have regulatory roles (e.g., acting as decoys for regulatory RNAs), but no such function is established for this gene. RPL36AP40 is not considered a therapeutic target, receptor, enzyme, transporter, or biomarker. There are no known drugs, mechanisms of action, disease associations, or safety concerns related to this specific pseudogene.
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