Ribosomal protein L36a pseudogene 48 (RPL36AP48)

RPL36AP48, or ribosomal protein L36a pseudogene 48, is a processed pseudogene identified in the human genome[4][5][8][10]. It is related by sequence to the functional ribosomal protein L36a (RPL36A), which is a structural component of the 60S ribosomal subunit, but RPL36AP48 itself does not encode a functional protein. Pseudogenes like RPL36AP48 do not translate into functional proteins; their sequences may sometimes regulate the expression of related protein-coding genes at the RNA level (e.g., via miRNA decoy or siRNA mechanisms), but there is no evidence or specific function documented for this particular pseudogene[2][5][8]. The gene is located on chromosome 17, recognized by identifiers such as HGNC:36721 and Ensembl:ENSG00000213180[4][8][10]. There are no known implications for therapeutic targeting, drug interactions, or biomarker status for RPL36AP48. Its biological and disease relevance is likely limited to basic genomic studies of pseudogene regulation and ribosomal gene evolution. In contrast, its functional relatives, RPL36A and RPL36AL, are active ribosomal protein genes involved in protein synthesis and cellular proliferation[1][3][7][11].

Other names

RPL36A_23_1571RPL36AP48