Target intelligence / Profile preview

Ribosomal protein L36a pseudogene 6 (RPL36AP6)

Target
RPL36AP6
Molecular classification
Other (Pseudogene)
01

Overview

RPL36AP6 is a human pseudogene, officially named "ribosomal protein L36a pseudogene 6". It is a noncoding genomic sequence with high similarity to the protein-coding RPL36A gene, which encodes a structural ribosomal protein of the 60S subunit. However, RPL36AP6 itself does not produce a functional protein, and its role is typically considered limited to possible noncoding RNA-related regulation (such as involvement in microRNA or siRNA pathways), though no specific regulatory function has been directly demonstrated for this pseudogene. It is not considered a therapeutic target, nor does it have established disease associations, known drug interactions, or biomarker utility. Its most common aliases are RPL36A_12_1002 and bA380I20.1.

Other names
RPL36A_12_1002bA380I20.1
02

Mechanism of action

None (No known mechanism of action for drugs targeting this pseudogene)

03

Biological functions

Potential regulatory roles via noncoding RNA mechanisms, but no direct involvement in coding protein functionPseudogene transcripts can sometimes participate in regulatory functions such as acting as miRNA decoys or producing siRNAs that modulate gene expressionThere is no direct experimental evidence for RPL36AP6 itself aside from being classified as a pseudogene
04

Disease associations

Other (No direct disease associations specific to RPL36AP6 pseudogene)Its parent protein (RPL36A) is associated with cancer and other diseases, but the pseudogene is not
05

Safety considerations

None (No relevant safety concerns as there are no therapeutic agents that directly target RPL36AP6)

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