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Ribosomal protein L37 pseudogene

Molecular classification
Pseudogene, Other
01

Overview

Ribosomal protein L37 pseudogene refers to a genomic DNA sequence homologous to the functional ribosomal protein L37 gene but rendered nonfunctional due to mutations or the absence of necessary regulatory elements[1][3]. Pseudogenes like this resemble their parent functional genes in sequence but do not produce a functional protein product and are largely considered "genomic fossils" or nonfunctional relics[1][3]. Although most pseudogenes are not translated, they may sometimes be transcribed into RNA at low levels, rarely resulting in regulatory effects. Pseudogenes are commonly annotated in genomes alongside their functional counterparts and can complicate molecular studies due to their sequence similarity to real genes[3]. The specific entity ENSG00000243423 is classified as a pseudogene and is not considered a therapeutic target, enzyme, receptor, or drug target. Key notes: - This is not a receptor, enzyme, transporter, or other canonical drug target. - There may be multiple ribosomal protein L37 pseudogenes in the human genome; they are named by the parent gene with suffixes or numbers (e.g., RPL37P1, RPL37P2), but all denote nonfunctional pseudogenized copies[2]. - Pseudogenes do not have known direct biological functions or disease roles, except in rare cases involving regulatory RNA functions[3][5]. - No drugs target these pseudogenes, and no biomarker or safety information is relevant. - The entry is marked as incorrect as a drug target by conventional standards.

Other names
RPL37Pribosomal protein L37 pseudogeneribosomal protein L37 pseudogene family

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