Ribosomal protein L44 pseudogene

This entry is a pseudogene—a genomic DNA sequence similar to a functional ribosomal protein gene, specifically L44, but is nonfunctional because of disabling mutations or regulatory defects. Pseudogenes cannot encode functional proteins and are generally considered "genomic fossils" or remnants of gene duplication or retrotransposition events[5][3]. Some pseudogenes can have regulatory effects or rarely encode peptides with novel functions, but such effects are not established for this specific pseudogene[1][7]. Additional clarification: - Ribosomal protein L44 itself is not an official human gene name; the homologous human ribosomal protein is encoded by RPL36A (ribosomal protein L36a), which was previously confused or referred to as L44 in older literature, but the current nomenclature does not include a protein called ribosomal protein L44 in humans[8]. - ENSG00000220643 represents a pseudogene record, not a gene encoding a therapeutic target protein. A pseudogene is not a targetable receptor, enzyme, transporter, or protein, and does not possess druggability or canonical biological roles expected of typical drug discovery targets[1][5][3]. If your interest is in the functional ribosomal protein, refer to RPL36A (ribosomal protein L36a)[8]. This entry is best classified as non-functional (is_target: false, is_incorrect: true) for pharmacological or therapeutic investigations.

Other names

RPL44P