Ribosomal protein L5 pseudogene 24 (RPL5P24)

Ribosomal protein L5 pseudogene 24 (RPL5P24) is a non-functional, processed pseudogene corresponding to the ribosomal protein L5 gene. Pseudogenes like RPL5P24 are segments of DNA that resemble functional genes but have accumulated mutations (such as frameshifts or premature stop codons) that prevent them from being expressed as functional proteins[2][8]. RPL5P24 is cataloged in gene and genome resources (for example, NCBI Gene: 100270841) and is one of several pseudogenes related to RPL5, but it does not contribute to known cellular functions, has no established role in pathophysiology, and is not a therapeutic or molecular target[2][8]. RPL5 (not the pseudogene) is a component of the large ribosomal subunit (60S) and participates in protein synthesis as well as extra-ribosomal roles in cell cycle regulation and tumor suppression[1][4][7]. Pseudogenes like RPL5P24 arise via duplication or retrotransposition events, resulting in gene-like sequences that remain in the genome but are generally transcriptionally inactive and non-functional[8]. Such pseudogenes are not considered functional targets for therapeutics, receptors, enzymes, or biomarkers, and their presence is primarily of bioinformatic interest or for evolutionary studies[8].

Other names

RPL5P24RPL5_9_935

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