Ribosomal protein L5 pseudogene 26 (RPL5P26)

Ribosomal protein L5 pseudogene 26 (RPL5P26) is a processed pseudogene—a non-functional genomic sequence resembling the ribosomal protein L5 (RPL5) gene. Unlike its parent gene, RPL5P26 does not encode a functional protein and typically has no biological activity. There are many processed pseudogenes of ribosomal proteins scattered throughout the genome; they are typically regarded as genomic fossils with no direct involvement in cellular function or disease. RPL5P26 is not a therapeutic target, receptor, enzyme, or transporter[5]. Context and clarification: - Pseudogenes like RPL5P26 are genomically similar to protein-coding genes but usually lack protein-coding potential due to disabling mutations or the absence of regulatory elements required for expression[5]. - The functional gene RPL5 (Ribosomal protein L5) is essential for ribosome assembly and has disease relevance, but pseudogenes such as RPL5P26 do not share these properties[1][4]. - Based on gene databases, RPL5P26 lacks evidence for functional protein expression, disease involvement, or druggability, thus should not be listed as a therapeutic target[5].

Other names

RPL5_13_1059RPL5P26