Ribosomal protein L5 pseudogene 4 (RPL5P4)

Ribosomal protein L5 pseudogene 4 (RPL5P4) is a processed pseudogene derived from the parent gene ribosomal protein L5 (RPL5). While the functional RPL5 protein is an essential component of the 60S ribosomal subunit involved in ribosome biogenesis, cell cycle regulation, and tumor suppression[1][2][3], the RPL5P4 pseudogene itself does not code for any protein or functional RNA. Pseudogenes like RPL5P4 are genomic DNA sequences that resemble known genes but lack the ability to produce functional products due to mutations, insertions, or deletions that disrupt normal transcription and translation[3][1]. The clinical and biological importance is specific to the functional RPL5 gene; pseudogenes are generally not considered as therapeutic targets and do not play roles as biomarkers or in disease mechanisms[3][1][2]. If you meant the parent gene/protein RPL5, consult ribosomal protein L5 information instead—it is a validated therapeutic, biomarker, and disease-associated target[1][2][3]. The naming conventions, aliases, and disease relevance (Diamond-Blackfan anemia, cancer, etc.) apply to RPL5, not RPL5P4.

Other names

RPL5_1_31RPL5P4