Ribosomal protein L6 pseudogene 14 (RPL6P14)

Ribosomal protein L6 pseudogene 14 (RPL6P14) is classified as a processed pseudogene in the human genome, derived from the functional ribosomal protein L6 (RPL6). Processed pseudogenes are genomic DNA sequences that resemble known genes but are typically non-functional due to mutations, truncations, or lack of essential regulatory elements. RPL6P14 does not encode a functional protein, does not participate in ribosomal biogenesis, and has not been implicated in any disease mechanism, drug interaction, or as a validated biomarker. It is listed as a gene feature in genome databases, primarily for annotation and comparative genomics purposes[3][6]. RPL6P14 is one of several pseudogenes derived from the parent gene RPL6, which encodes the 60S ribosomal protein L6—a structural ribosomal constituent with well-defined functions in protein synthesis[1][7]. RPL6P14, however, lacks coding capacity and is not expressed as a functional protein. It is not associated with enzymatic activity, receptor function, transporter activity, or transcription factor roles[3][6]. Pseudogenes like RPL6P14 are generally omitted from lists of drug targets and disease biomarkers; they are useful mostly for genetic studies of genome evolution and annotation, rather than molecular targeting or therapy[6]. RPL6P14 is a non-coding pseudogene, not a valid therapeutic target, and should not be mistaken for the functional ribosomal protein L6, which does play significant biological roles as a ribosomal constituent.

Other names

RPL6_2_505RPL6P14