Ribosomal protein L7a pseudogene 54 (RPL7AP54)

Ribosomal protein L7a pseudogene 54 (RPL7AP54) is a retrocopy of the functional ribosomal protein L7a (RPL7A) gene. Pseudogenes such as RPL7AP54 are non-coding DNA segments originating from functional genes but lacking protein-coding ability due to mutations or incomplete sequences. While most processed pseudogenes have no biological function, some can acquire regulatory capabilities or rare neofunctionalization. RPL7AP54 is considered nonfunctional in humans and shows homology to its parent gene but is not a protein, enzyme, receptor, or direct drug target[1][2][4][5]. RPL7AP54 is a nonfunctional pseudogene and not considered a druggable or therapeutic target. It is important to distinguish this processed pseudogene from its parental gene RPL7A, which is a bona fide member of the ribosomal protein family and is associated with the ribosome’s structural and regulatory functions[3][7].

Other names

RPL7A_22_1161RPL7AP54