Ribosomal protein L9 pseudogene (RPL9P26)

Ribosomal protein L9 pseudogene (RPL9P26, ENSG00000242793) is a non-coding genomic sequence related to the gene encoding ribosomal protein L9, a structural constituent of the 60S ribosomal subunit involved in ribosome biogenesis and protein synthesis[1][5]. As a pseudogene, RPL9P26 lacks the ability to code for a functional protein and is considered non-functional under biological and pharmacological definitions[7]. While the protein-coding gene RPL9 is a research and emerging therapeutic target in some cancers and ribosomopathies[5], RPL9P26 and other ribosomal pseudogenes have no established biological or disease-modifying role. Pseudogenes may sometimes regulate their parent genes at the RNA level in rare contexts, but there is no evidence of such function for RPL9P26[6]. No drugs, mechanisms of action, or biomarkers are associated with this pseudogene. Clarifying note: - This entry corresponds to a pseudogene, not a functional protein or therapeutic target. It is important not to conflate pseudogenes with their parental protein-coding genes (such as RPL9, which is functional)[1][5]. - If you need information on the functional ribosomal protein L9 (RPL9, not the pseudogene), please specify, as RPL9 is distinct and does have disease and drug relevance[5].

Other names

RPL9_11_1421RPL9P26ENSG00000242793