Ribosomal protein L9 pseudogene 21 (RPL9P21)

Ribosomal protein L9 pseudogene 21 (RPL9P21) is a processed pseudogene in the human genome related to the ribosomal protein L9 gene, which encodes a component of the 60S ribosomal subunit involved in cellular protein synthesis. Pseudogenes such as RPL9P21 are genomic DNA sequences derived from functional genes that have lost their protein-coding capacity or regulatory elements due to mutation, truncation, or other genomic rearrangement. They are generally not expressed as functional proteins and do not participate in cellular processes or disease, though some pseudogenes can be transcribed and have regulatory roles in rare circumstances. There is no evidence that RPL9P21 plays an active biological, therapeutic, or disease role. The functional parent gene, RPL9, is associated with diseases (such as Diamond-Blackfan anemia) and is a bona fide ribosomal protein, but this does not extend to the pseudogene. Commercial databases (such as Sigma-Aldrich) index RPL9 pseudogenes for research, but do not list drugs or biological assays specific to RPL9P21. Listings for RPL9 pseudogenes in genome databases serve mostly as genomic reference information, not as molecular targets.

Other names

RPL9P-21

None. No drugs target or modulate RPL9P21.