Ribosomal protein L9 pseudogene 5 (RPL9P5)

Ribosomal protein L9 pseudogene 5 (RPL9P5) is a processed pseudogene related to the functional ribosomal protein L9 gene (*RPL9*). Pseudogenes such as RPL9P5 are non-coding genomic elements that originate from duplication or retrotransposition events of their parent gene and typically do not produce a functional protein product[1][6]. RPL9P5 only shares sequence similarity with the active RPL9 gene but lacks evidence for protein expression or biological function. The functional RPL9 protein is a component of the 60S subunit of the cytoplasmic ribosome and is involved in protein translation, but RPL9P5 does not contribute to ribosome structure or activity[1][5][3]. There are multiple processed pseudogenes of ribosomal protein genes present throughout the genome, and they are not considered therapeutic targets, nor are there drugs or biomarker applications associated with RPL9P5[1][6]. RPL9P5 is not a therapeutic target such as a receptor, enzyme, transporter, or transcription factor. No evidence at this time suggests RPL9P5 has regulatory roles or pathogenic involvement. The distinction between the functional ribosomal protein L9 (RPL9) and its pseudogenes is important; RPL9 is a bona fide ribosomal protein, while RPL9P5 is a non-functional pseudogene[1][5][3][6].

Other names

RPL9P5ribosomal protein L9 pseudogene 5Human RPL9P5 (100129179)