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Ribosomal protein lateral stalk subunit P0 pseudogene 12 (RPLP0P12)

Target
RPLP0P12
Molecular classification
Other (Pseudogene; non-coding RNA-related element)
01

Overview

RPLP0P12 is a processed pseudogene in the human genome, corresponding to the ribosomal protein lateral stalk subunit P0 gene. While the functional parental gene RPLP0 encodes a protein of the ribosomal 60S subunit[1][3][5], RPLP0P12 itself does not produce a protein. This pseudogene may have potential non-coding regulatory roles by influencing gene expression, as some pseudogenes do, but there are no specific functional, disease, or therapeutic associations currently documented for RPLP0P12[9][10][2][4][6]. Its canonical genomic name is Ribosomal protein lateral stalk subunit P0 pseudogene 12, abbreviated RPLP0P12, and it should not be confused with the functional ribosomal protein Lateral Stalk Subunit P0 (RPLP0), which is associated with ribosome function and diseases like Diamond-Blackfan Anemia[1][5]. If you need information on the actual therapeutic target (RPLP0—the protein), specify "ribosomal protein lateral stalk subunit P0" rather than "pseudogene 12". RPLP0P12 is a non-coding pseudogene and not a drug target.

Other names
Ribosomal protein lateral stalk subunit P0 pseudogene 12RPLP0P12
02

Mechanism of action

Not applicable; pseudogenes do not produce protein and have no direct mechanism targeted by drugs

03

Biological functions

May participate in regulation of gene expression via non-coding RNA mechanisms, such as acting as miRNA decoys or impacting RNA stability (general for pseudogenes; specific function for RPLP0P12 not reported)
04

Disease associations

Other (General pseudogene roles in cancer and cell biology described for some pseudogenes, but no direct association or evidence for RPLP0P12 specifically)

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