Ribosomal protein S10 pseudogene 28 (RPS10P28)

Ribosomal protein S10 pseudogene 28 (RPS10P28) is a processed pseudogene related to the functional ribosomal protein S10 (RPS10) gene found in humans[1][4][6]. Pseudogenes are genetic elements that resemble protein-coding genes but have lost their coding or regulatory potential due to mutations and are typically nonfunctional. RPS10P28 does not code for a functional protein and is not considered a biological or therapeutic target[1][4][6][9]. There is no evidence for participation in disease, biological processes, or drug interactions. The functional RPS10 protein is a component of the 40S subunit of cytoplasmic ribosomes, essential for protein synthesis, but RPS10P28 itself has no active molecular function. Key clarifications and context: Is this a therapeutic target? No; RPS10P28 is a pseudogene, not a protein, receptor, enzyme, or other actionable target in drug discovery or clinical settings[1][4][9]. Is there something wrong with this target? Yes; identifying RPS10P28 as a molecular target is incorrect, as it does not have a functional product or role amenable to therapeutic intervention[1][9]. Distinction from RPS10: The functional protein-coding gene is RPS10 (ribosomal protein S10), which does have a biological role in the ribosome and has clinical relevance in disorders such as Diamond-Blackfan anemia[5][7]. RPS10P28 is just one of many dispersed processed pseudogenes of RPS10 in the human genome[1][6][9]. Summary: "Ribosomal protein S10 pseudogene 28" (RPS10P28) is a non-functional, processed pseudogene without known biological activity or disease association, and is not a valid therapeutic or diagnostic target[1][4][6][9].

Other names

RPS10_14_1658