Ribosomal protein S12 pseudogene 24 (RPS12P24)

RPS12P24 is a processed pseudogene derived from the **ribosomal protein S12** gene (RPS12). Pseudogenes are genomic DNA sequences similar to normal genes but nonfunctional; they result from gene duplication or retrotransposition events followed by disabling mutations that prevent protein expression[8]. RPS12P24 does not produce a protein nor does it encode any known biological function or disease association. While its parent gene, ribosomal protein S12, is essential for ribosomal function and protein synthesis[5][6], RPS12P24 itself is considered *genomic "junk"* or "dead" gene sequence with no role as a therapeutic target, biomarker, or disease-relevant molecule[8]. For molecular targeting, functional RPS12 would be the relevant entity—not its pseudogene copies dispersed throughout the genome[5][6][7][8]. **Detailed context on parent gene (RPS12):** - RPS12 encodes ribosomal protein S12, which is a structural component of the small 40S ribosomal subunit and functions in translation, codon recognition, and accuracy of protein synthesis[1][5][6]. - The human genome contains many processed pseudogenes of ribosomal protein genes, including RPS12P24, which typically do not have coding or regulatory functions[8]. - Pseudogenes may occasionally play minor roles in gene regulation or genome evolution, but RPS12P24 has no evidence supporting such a role as of current knowledge[8]. **Summary:** RPS12P24 is a noncoding pseudogene, not a therapeutic target, receptor, or functional molecule. There is nothing functionally actionable, disease-associated, or druggable about this pseudogene. Its inclusion as a "target" would be incorrect[7][8].

Other names

RPS12_12_1308RPS12P24