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Ribosomal protein S14 pseudogene 8 (RPS14P8) is a human pseudogene related to the canonical ribosomal protein S14 gene (RPS14)[2][7]. Pseudogenes like RPS14P8 arise from duplication events or retrotransposition and resemble their parent genes in sequence but typically lack protein-coding capability and functional expression. RPS14P8 is classified as a processed pseudogene, meaning it does not encode a functional protein and is not involved in translation or ribosome function. Unless there is independent evidence of transcription or involvement in disease, RPS14P8 itself is not considered a therapeutic target, receptor, enzyme, transporter, or a biomarker[2][7]. Its name is sometimes confused with functional ribosomal protein S14, which plays a role in ribosomal assembly and has been studied as a potential biomarker or therapeutic target in some cancers[5][6], but RPS14P8 does not share these properties. Key notes: - RPS14P8 is a pseudogene, not a receptor, enzyme, transporter, or direct therapeutic target[2][7]. - There is no evidence it has biological function, disease association, or drug interaction. - Information about RPS14 (without 'P8') should not be attributed to RPS14P8 unless specifically indicated, so listing RPS14P8 as a drug target or biomarker would be incorrect for structured data extraction.
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