Ribosomal protein S15a pseudogene 17 (RPS15AP17)

Ribosomal protein S15a pseudogene 17 (RPS15AP17) is an annotated processed pseudogene in the human genome[1][6][7]. Pseudogenes are genomic sequences that resemble known genes but have accumulated mutations (such as frameshifts or premature stop codons) that prevent them from encoding functional proteins[5]. RPS15AP17 is related by sequence to the functional ribosomal protein S15a gene but does not produce a protein or have a biological role in the cell. Such pseudogenes are common in the human genome, especially among ribosomal protein families, owing to their history of retrotransposon-mediated duplication and mutational decay[5]. While some pseudogenes can regulate their parent genes under specific conditions by acting as competing endogenous RNAs, there is currently no evidence that RPS15AP17 does so[1][5][9]. Key points: - RPS15AP17 encodes a pseudogene, not a protein. - It is not recognized in biomedical literature as a receptor, enzyme, drug target, or biomarker. - No drugs, disease roles, or safety concerns are relevant because the locus is considered genomically inert[1][5][6]. - Most data sources list it for genome annotation purposes only[1][4][6].

Other names

RPS15A_8_485RPS15AP17