Ribosomal protein S15a pseudogene 25 (RPS15AP25)

Ribosomal protein S15a pseudogene 25 (RPS15AP25) is a processed pseudogene in the human genome, derived from the parental ribosomal protein S15a gene (RPS15A)[1][2]. It does not encode a functional protein and is not involved in known canonical biological pathways. Like other processed pseudogenes, it originated from retrotransposition of an mRNA transcript of the parent gene and typically lacks introns[4]. Pseudogenes, including RPS15AP25, generally do not have direct biological or disease associations, though emerging research suggests some pseudogenes may play regulatory roles at the RNA level, such as serving as microRNA decoys or being sources of regulatory RNAs[4]. RPS15AP25 has no reported role in disease, no known therapeutic or biomarker functions, and is not considered a conventional target for drug discovery or therapy[1][2][4]. Key clarification: RPS15AP25 should not be confused with its protein-coding parental gene RPS15A, which encodes the ribosomal protein S15a, a component of the 40S ribosomal subunit with established roles in ribosome function and certain anemias[3][5]. No evidence was found for clinical, therapeutic, or biomarker relevance of RPS15AP25.

Other names

RPS15A_14_912RPS15AP25

None (not therapeutically targeted).