Ribosomal protein S15A pseudogene 29 (RPS15AP29)

Ribosomal protein S15A pseudogene 29 (RPS15AP29) is a non-functional processed pseudogene related to the gene encoding ribosomal protein S15a, which is a component of the 40S ribosomal subunit responsible for catalyzing protein synthesis in eukaryotic cells[3][5]. Like most ribosomal protein pseudogenes, RPS15AP29 does not encode a functional protein and is not considered a therapeutic target, enzyme, transporter, receptor, or other actionable biological target[5]. Its presence reflects historical gene duplication and retrotransposition events in evolution; it has no current translational or clinical utility.\n\nMost ribosomal protein pseudogenes are interspersed throughout the human genome and may sometimes be mistaken for functional genes due to high sequence similarity, but nearly all lack functionality due to disabling mutations or lack of expression[5]. There is no evidence that RPS15AP29 produces a functional transcript or protein, nor is it implicated in any signaling, regulatory, or disease-related pathways.\n\nSummary of assessment for target information:\n- RPS15AP29 is a pseudogene without biological activity and is not druggable nor functionally involved in human disease or signaling.\n- This entry is not appropriate as a therapeutic or biological target (is_target: false).\n- Listing it as a target may be an error (is_incorrect: true) because pseudogenes should generally not be included in target lists unless novel function has been demonstrated.\n- There are no interacting drugs, disease associations, biomarker status, or safety concerns relevant to this pseudogene.

Other names

RPS15A_17_1092RPS15AP29