Ribosomal protein S16 pseudogene 4 (RPS16P4)

Ribosomal protein S16 pseudogene 4 (RPS16P4) is a nonfunctional, processed pseudogene related to the ribosomal protein S16 gene family. It arose from a duplication event followed by the loss of protein-coding potential, and does not contribute to ribosomal protein synthesis or known biological functions. Pseudogenes like RPS16P4 are generally transcriptionally inactive and are not involved in disease, biological pathways, or drug interaction; their primary significance is in genome structure and evolution studies[1][2][8]. #### Important Clarification - **RPS16P4 is not a functional gene or protein target,** and there is no evidence it is biologically active or relevant to therapeutic drug targeting[1][2][8]. - The actual protein-coding gene in this family, **RPS16 (ribosomal protein S16)**, is a component of the small (40S) ribosomal subunit and plays a critical role in protein synthesis[4][5][6]. - Numerous processed pseudogenes of ribosomal protein genes, including RPS16, are found scattered throughout the genome. These generally lack introns, are transcriptionally inactive, and do not encode proteins[1][2][8]. - There is no evidence that RPS16P4 is misannotated or that it encodes any functional product. If you meant the actual ribosomal protein S16, please specify, as it is a structurally and functionally important part of the ribosome, but **RPS16P4 itself is not**.

Other names

RPS16_2_363RPS16P4