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Ribosomal protein S2 pseudogene 2 (RPS2P2) is one of multiple processed pseudogenes in the human genome derived from the ribosomal protein S2 gene (RPS2)[2][3]. Pseudogenes like RPS2P2 share high sequence similarity to their parent genes but are typically non-functional due to disabling mutations, truncations, or lack of regulatory elements necessary for protein expression[2]. These pseudogenes arise through retrotransposition and are widely distributed across the genome, often serving as genomic structural elements or contributing to genetic evolution, but do not encode functional proteins or serve as therapeutic targets. The parent gene, RPS2, encodes a component of the 40S ribosomal subunit with essential roles in protein biosynthesis[1][3].
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