Ribosomal protein S2 pseudogene 45 (RPS2P45)

Ribosomal protein S2 pseudogene 45 (RPS2P45) is a human processed pseudogene, most likely originating from retrotransposition of the mRNA from the functional RPS2 gene, which encodes a protein of the 40S ribosomal subunit. RPS2P45 does not produce a functional protein, typically contains disablements like frameshifts or premature stop codons, and may show sequence homology to RPS2. While some pseudogenes are transcribed and may generate regulatory noncoding RNAs, there is no reported functional or disease relevance for RPS2P45. The classification as a pseudogene is supported by genomic and evolutionary analysis, indicating that such elements are primarily remnants of gene duplication and retrotransposition events.

Other names

FLJ12331RPS2_21_1492RPS2P45

Not applicable; pseudogenes do not encode functional protein or receptor targets for drug action