Ribosomal protein S26 pseudogene 43 (RPS26P43)

Ribosomal protein S26 pseudogene 43 (RPS26P43) is a processed pseudogene corresponding to the gene encoding ribosomal protein S26, a component of the small 40S ribosomal subunit involved in protein synthesis[3][5]. Pseudogenes like RPS26P43 do not produce functional proteins due to mutations or truncations in their sequences, and they are generally considered non-functional genomic elements. The functional RPS26 gene (not its pseudogenes) is involved in ribosome biogenesis, RNA binding, and has been linked to conditions such as Diamond-Blackfan anemia[5][6]. Multiple processed pseudogenes—including RPS26P43—are dispersed throughout the human genome, but these pseudogenes are not themselves considered therapeutic targets[3][5][6]. Explanation for "is_incorrect": While RPS26 (ribosomal protein S26) is a protein-coding gene with biological significance and a potential disease role, RPS26P43 denotes a pseudogene, which by definition is not biologically active as a receptor, enzyme, or therapeutic target. As such, it does not fit the conventions for a molecular target used in drug discovery or biology; listing it as a therapeutic target would be incorrect[2][3][4][5][6].

Other names

RPS26 pseudogene 43ribosomal protein S26 pseudogene 43RPS26P43