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Ribosomal protein S26 pseudogene 55 (RPS26P55) is a pseudogene located in the human genome that shares homology with the protein-coding ribosomal protein S26 gene (RPS26)[5][6][7]. Unlike its parent gene, RPS26P55 lacks protein-coding capability and has no confirmed biological function or involvement in disease. It is sometimes mistakenly conflated with RPS26, which plays vital roles in ribosome assembly, protein synthesis, cell cycle regulation, and is associated with Diamond-Blackfan anemia—however, these functional and pathological features do not apply to the RPS26P55 pseudogene[1][3][4]. Important clarification: RPS26P55 is a pseudogene and should not be confused with the canonical ribosomal protein S26 (RPS26), a well-characterized ribosomal protein essential for cellular function and implicated in disease[1][3][4]. If your intent is to study druggability, therapeutic targeting, biological function, or disease relevance, RPS26P55 does not meet any of those criteria. Use "Ribosomal protein S26" (RPS26) for information pertaining to the validated protein-coding gene and its biomedical implications.
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