Ribosomal protein S27 pseudogene 1 (RPS27P1)

Ribosomal protein S27 pseudogene 1 (RPS27P1) refers specifically to a *processed pseudogene* of the ribosomal protein S27 gene, not to a protein-coding gene or an expressed receptor, enzyme, or validated druggable target. Processed pseudogenes arise from the reverse transcription and integration of a processed mRNA back into the genome, but they typically lack regulatory elements needed for expression and do not produce functional proteins[5][2]. Ribosomal protein S27 (encoded by RPS27, not RPS27P1) is a component of the 40S ribosomal subunit involved in protein synthesis and exhibits roles in DNA binding, ribosome structure, and zinc ion binding[1][6]. The pseudogene RPS27P1, however, does not encode an active protein and has no demonstrated biological function, disease association, or drug interactions. Its designation as a pseudogene indicates it is a non-functional relic—therefore, it is not a therapeutic target, nor are any drugs or disease roles known for it. Multiple processed pseudogenes exist for many ribosomal proteins (including RPS27) in the human genome[5]. Recent functional studies involving ribosomal protein S27 and its paralog RPS27L have not implicated RPS27P1 in any biological process, regulatory role, or mechanism of disease[2][4]. RPS27P1 is not a therapeutic target but rather a genomic pseudogene with no known function or disease linkage[5]. All data related to therapeutic targeting, interacting drugs, or biological/disease mechanisms refer to the functional RPS27 gene or its close paralog RPS27L, not to its pseudogenes.

Other names

bA108M11.3RPS27_10_1079RPS27P1