Ribosomal protein S27 pseudogene 12 (RPS27P12)

Ribosomal protein S27 pseudogene 12 (RPS27P12) is a processed pseudogene, not coding a functional protein, and is one of several pseudogenes derived from the active ribosomal protein S27 gene. Pseudogenes do not produce functional protein products and are not known to play direct biological roles. They are often catalogued for genomic annotation but are not considered therapeutic targets or functional biomolecules[2][5][7]. Context and supporting details: - RPS27P12 is annotated in genomic databases as a pseudogene, meaning it is a non-functional copy or derivative of the true ribosomal protein S27 gene (RPS27)[2][5][7]. - The canonical, functional gene is RPS27, which encodes a component of the 40S ribosomal subunit involved in protein synthesis, and has evidence linking it to cancer and ribosome function[3][6][8]. - RPS27P12 itself does not encode a protein, has no described function, does not interact with drugs, and plays no known role in disease or as a biomarker[2][5][7]. - Pseudogenes like RPS27P12 are plentiful for ribosomal proteins and typically arise from gene duplication or retrotransposition events[3][4][6]. - If a query is about RPS27P12 as a therapeutic target, it is incorrect: RPS27P12 is not a drug target and has no therapeutic relevance. Summary of key findings: RPS27P12 is not a functional target, not a receptor or enzyme, and has no curated biological or clinical function. It is a pseudogene, and while RPS27 (its parent gene) is functionally important, RPS27P12 itself is not. Therefore, if this pseudogene was selected as a "target", that would be a mistake[2][5][7].

Other names

RPS27_4_403[5][7]