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Target intelligence / Profile preview
Ribosomal protein S27 pseudogene 22 (RPS27P22)
- Target
- RPS27P22
- Molecular classification
- Other (Pseudogene)
01
Overview
Ribosomal protein S27 pseudogene 22 (RPS27P22) is a processed pseudogene in the human genome that shares high sequence similarity with the functional ribosomal protein S27 gene (RPS27) and its paralog RPS27L. While the functional protein participates in ribosome biogenesis and cellular translation and may play roles in cancer, the pseudogene itself does not encode an active protein and is not considered a valid therapeutic target. References to RPS27P22 should not be conflated with those for functional ribosomal protein S27 or S27L, which have studied roles in protein synthesis, cell growth, and disease[4][5][6].
- Other names
- RPS27P22ribosomal protein S27-like pseudogeneRPS27_12_1218
02
Mechanism of action
Not applicable; no known drugs targeting RPS27P22.
03
Biological functions
None established; pseudogenes typically do not encode functional products.
04
Disease associations
None demonstrated; related functional proteins (RPS27, RPS27L) are implicated in cancer and cell growth[4][5].
05
Safety considerations
Not applicable; pseudogenes are not direct therapeutic targets and pose no safety profile considerations.
06
Interacting drugs
None known for this pseudogene; drugs may act on RPS27 or its zinc finger domain in oncology, but not on RPS27P22[5].
07
Biomarkers
None for RPS27P22; expression of RPS27 and its paralogs may have biomarker significance in cancer[5].
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