Ribosomal protein S27 pseudogene 26 (RPS27P26)

Ribosomal protein S27 pseudogene 26 (RPS27P26) is a human pseudogene related in sequence to the protein-coding ribosomal protein S27 gene. Pseudogenes are segments of DNA that resemble functional genes but are generally nonfunctional; RPS27P26 does not code for a protein and lacks demonstrated biological function or therapeutic relevance. Multiple such ribosomal protein pseudogenes exist in the genome, typically arising from gene duplication or retrotransposition events and subsequently acquiring disabling mutations that prevent their expression as functional proteins. RPS27P26 is not a functional gene, enzyme, receptor, transporter, or typical drug target. It is a processed pseudogene and should not be confused with the active ribosomal protein S27 gene (RPS27), which codes for a component of the ribosomal 40S subunit and may have clinical importance in cancer and anemia. is_incorrect=true is marked because this pseudogene is not itself a therapeutic target—therapeutically relevant information pertains to its parent gene (RPS27), not the pseudogene. No drugs, mechanisms of action, biomarker roles, or safety issues are associated with pseudogenes like RPS27P26. Aliases mentioned, such as "RPS27_12_1494" and "ribosomal protein S27-like pseudogene," are alternative gene database identifiers and descriptors.

Other names

RPS27_12_1494Ribosomal protein S27-like pseudogeneRPS27P26