Ribosomal protein S27 pseudogene 27 (RPS27P27)

Ribosomal protein S27 pseudogene 27 (RPS27P27) is a **processed, non-coding pseudogene** of the gene encoding ribosomal protein S27. Unlike the parent RPS27 gene, which encodes a component of the 40S ribosomal subunit important in protein synthesis and has been implicated as an oncogene and a cancer biomarker, RPS27P27 itself is not transcribed or translated into a functional protein and does not participate in cellular processes or disease pathogenesis[3][6]. Multiple processed pseudogenes of ribosomal proteins, including RPS27, exist in the human genome; however, these pseudogenes generally lack coding capacity and are not considered therapeutic or drug targets[3][6].\n\n**Key points and explanations:**\n- RPS27P27 is listed in gene databases as a pseudogene, not as a functional gene or protein[3][6].\n- Pseudogenes do not produce proteins and do not have established biological functions or roles in disease; they are not therapeutic targets.\n- While *RPS27* gene (not the pseudogene) encodes a protein component of the ribosome and is involved in cancer biology, RPS27P27 does not encode this or any other protein[1][5].\n\n**Incorrectness explanation:**\nRPS27P27 is not a **therapeutically relevant target**, nor does it encode a protein, enzyme, receptor, transporter, or any functional molecule. Any confusion may arise from the similarity of its name to the functional gene RPS27. This target is a pseudogene and not suitable as a canonical therapeutic target[3][6].

Other names

RPS27_15_1487ribosomal protein S27-like pseudogeneRPS27P27