Target intelligence / Profile preview

Ribosomal protein S27a pseudogene

Molecular classification
Pseudogene, Other
01

Overview

A ribosomal protein S27a pseudogene is a *non-functional genomic copy* derived from the RPS27A gene, which normally encodes a critical 40S ribosomal subunit protein involved in protein synthesis and ubiquitin precursor processing[1][2][3][5]. Pseudogenes generally do not produce functional proteins nor participate in known regulatory or pathological roles, although rare exceptions of pseudogene protein expression exist for some families[7]. Ribosomal protein S27a pseudogenes are classified as *pseudogenes*, not as receptors, enzymes, or typical therapeutic targets[7]. The term "ribosomal protein S27a pseudogene" is not a canonical target name in drug discovery or clinical diagnostics.

Other names
RPS27A pseudogeneribosomal protein S27a, pseudogene 1LOC100912032Uba52Ubb
02

Biological functions

The pseudogene itself has no recognized biological function; functional RPS27A encodes a ribosomal protein involved in protein synthesis
03

Disease associations

Ribosomal protein S27a (not the pseudogene) is linked to Diamond-Blackfan anemia and progressive supranuclear palsy; the pseudogene has no established disease associations

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