Target intelligence / Profile preview

Ribosomal protein S27a pseudogene 17 (RPS27AP17)

Target: RPS27AP17
Molecular classification: Other (Pseudogene), Not a member of functional molecular families like enzyme, receptor, or transcription factor

Overview

RPS27AP17 is a **processed pseudogene** derived from the RPS27A gene, which codes for **ribosomal protein S27a**. The parental RPS27A gene encodes a fusion protein comprising **ubiquitin** and the ribosomal protein S27a, a component of the **40S ribosomal subunit** with roles in protein synthesis and cellular stress response[1][3][2]. However, RPS27AP17 itself does not produce a functional protein—like most pseudogenes, it lacks coding ability and has no identified molecular or clinical function. Pseudogenes such as RPS27AP17 are often the result of genomic duplication or retrotransposition, but apart from occasional regulatory roles (not documented for RPS27AP17), they do not serve as molecular targets or disease genes[5].

Other names: RPS27A pseudogene 17RPS27AP17ribosomal protein S27a pseudogene 17

Mechanism of action

None (No drug mechanisms described; pseudogene, not an actionable target)

Biological functions

None (Pseudogenes generally lack canonical biological functions; the parental gene RPS27A encodes a ribosomal protein, but pseudogenes are generally non-functional)

Disease associations

None directly attributed (RPS27AP17 does not have a recognized role in disease as a pseudogene)

Safety considerations

None (No therapeutic applications, thus no safety issues)

Interacting drugs

None (No drugs known to interact with RPS27AP17; pharmacological targeting is not applicable for pseudogenes)

Biomarkers

None (Not used as a biomarker in patient selection or monitoring)

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