Ribosomal protein S3a pseudogene 14 (RPS3AP14)

Ribosomal protein S3a pseudogene 14 (RPS3AP14) is a processed pseudogene derived from the parent RPS3A gene, which encodes a ribosomal protein found in the 40S small ribosomal subunit in human cells[5]. Like most processed pseudogenes, RPS3AP14 does not encode a functional protein and does not participate in typical ribosomal or cellular processes. Its presence in the genome is the result of retrotransposition, and it is considered nonfunctional: it does not act as a receptor, enzyme, transporter, or other molecule with a therapeutic role[6]. Such pseudogenes may occasionally be transcribed, but this does not confer biological function, and they are not direct drug targets, biomarkers, or sources of safety concerns in therapeutic contexts. The parent gene, RPS3A, codes for a protein in the small 40S ribosomal subunit and is involved in protein synthesis, but its pseudogenes like RPS3AP14 are nonfunctional by definition[5][6]. The naming conventions of pseudogenes often refer to their parent gene and indicate their status as copies lacking function. Some pseudogenes serve as evolutionary or regulatory elements, but there is no evidence that RPS3AP14 has any such proven roles.

Other names

RPS3A pseudogene 14RPS3AP14RPS3A_7_401ribosomal protein S3a pseudogene 14