Ribosomal protein S4, X-linked pseudogene

This entry is a processed pseudogene for the human ribosomal protein S4, X-linked (RPS4X—functional gene) and does not encode a protein product nor is it considered a functional molecule or therapeutic target in humans[3][6]. Pseudogenes are often annotated in genomic databases as related to functional protein-coding genes, but they lack the ability to produce functional proteins due to sequence changes such as frameshifts, premature stop codons, or lack of promoter activity[6]. The functional gene is RPS4X (Ribosomal protein S4, X-linked)[1][3][5][7]. Pseudogenes like LOC100420532 are frequently annotated in genome browsers and gene lists, but do not represent active targets for drug discovery or therapeutic intervention. Due to the similarity in names, this pseudogene can incorrectly be cited when the functional gene/protein is meant. In literature and databases, the active, protein-coding RPS4X gene is sometimes conflated with its pseudogenes. The pseudogene itself is not a therapeutic target and has no documented interactions, functions, or biomarker usage, as is typical for pseudogenes. The functional RPS4X gene product (protein S4 of the small ribosomal subunit) can have disease relevance, but this does not apply to the pseudogene[1][3][5][7]. This entry should not be used for target curation or drug discovery work. If you are seeking the functional entity, refer to Ribosomal protein S4, X-linked (RPS4X), not its pseudogene[3][7].

Other names

LOC100420532ENSG00000251354