Target intelligence / Profile preview

Ribosomal protein S4X pseudogene 23 (RPS4XP23)

Target
RPS4XP23
Molecular classification
Other (pseudogene)
01

Overview

Ribosomal protein S4X pseudogene 23 (RPS4XP23) is a human pseudogene annotated by the HUGO Gene Nomenclature Committee, with HGNC ID: 48367[2]. Pseudogenes are genomic DNA sequences that resemble known genes but are generally non-functional because they have lost gene expression in the cell or do not encode functional proteins[8][1]. RPS4XP23 is not transcribed into a functional ribosomal protein; it is one of many processed pseudogenes derived from the ribosomal protein S4 gene family. There is no evidence that this pseudogene encodes a functional protein or that it acts as a therapeutic target[1][2][8]. RPS4XP23 is a pseudogene, not a protein-coding gene or actionable molecule[1][2][8]. It is not considered a therapeutic target and has no known roles in disease, biological function, or drug interaction[1][2]. This gene does not encode a functional protein and has no direct relevance as a biomarker or clinical safety concern[8]. The presence of the RPS4XP23 locus reflects the common genomic phenomenon where functional ribosomal protein genes, particularly those involved in the ribosome's small 40S subunit (such as RPS4X), have numerous processed pseudogenes scattered throughout the genome[1][8][5]. If you were seeking information on the functional ribosomal protein encoded by RPS4X (Ribosomal protein S4 X-linked), that is a separate, protein-coding gene involved in ribosome function and biology[4][10]. In this case, RPS4XP23 itself is not a true biological target but a relic of genomic evolution.

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