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Ribosomal protein S5 pseudogene 4 (RPS5P4) is a processed pseudogene in the human genome that shares sequence similarity with the functional ribosomal protein S5 gene but does not encode a functional protein or participate in ribosome assembly or protein synthesis. Like other pseudogenes, it is generally considered non-functional and is not implicated as a therapeutic target or biomarker in disease. Pseudogenes arise via gene duplication or retrotransposition and may have regulatory roles in rare cases, but there is no strong evidence for activity from RPS5P4.
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