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RPSAP1 is a processed pseudogene related to the functional ribosomal protein SA (RPSA, also known as 37/67 kDa laminin receptor), which is involved in ribosome structure and function, as well as acting as a cell surface receptor for laminin and participating in processes like cancer metastasis and prion disease[1][4]. Unlike the protein-coding RPSA gene, RPSAP1 does not encode a functional protein and is not known to serve as a drug target or biomarker. Pseudogenes like RPSAP1 may sometimes be transcribed, but there is no clear evidence of functional roles in protein synthesis or disease[4][7]. This information distinguishes the pseudogene (RPSAP1) from its highly homologous functional parent gene (RPSA), which has established roles in cancer biology, cell adhesion, infection, and the ribosome[1][4].
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