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Target intelligence / Profile preview
Ribosomal protein SA pseudogene 14 (RPSAP14)
- Target
- RPSAP14
- Molecular classification
- Other (Pseudogene)
01
Overview
Ribosomal protein SA pseudogene 14 (*RPSAP14*) is a processed pseudogene related to the functional *RPSA* gene, which encodes the ribosomal protein SA/laminin receptor. Pseudogenes like *RPSAP14* arise from duplication or retrotransposition events and typically do not encode active proteins. While some ribosomal protein pseudogenes are transcribed in certain tissues and can potentially have regulatory roles as non-coding RNAs, there is no evidence that *RPSAP14* has any such function. Studies on *RPSA* and its family of pseudogenes show that most, including *RPSAP14*, lack an intact open reading frame and contain mutations that prevent translation into a full-length functional protein. Therefore, *RPSAP14* is not a functional gene, receptor, or drug target, nor is it linked to any known therapeutic or diagnostic application.
- Other names
- LAMRP4LAMR1P14LAMRL4laminin receptor 1 pseudogene 14laminin receptor-like 4RPSAP14
02
Mechanism of action
None (no drugs known to target *RPSAP14*)
03
Biological functions
None confirmed; pseudogenes generally lack protein-coding function, though rare cases may exert regulatory roles as non-coding RNA, but this is not established for *RPSAP14*
04
Disease associations
None known; *RPSAP14* itself is not established to play a role in disease. The functional *RPSA* gene, not this pseudogene, is associated with cancer, prion diseases, and other pathologies
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