Ribosomal protein SA pseudogene 22 (RPSAP22)

Ribosomal protein SA pseudogene 22 (RPSAP22) is a processed pseudogene that is part of the *RPSA* gene family, which includes the gene encoding ribosomal protein SA (also known as 37-kDa laminin receptor precursor/67-kDa laminin receptor, LRP/LR)[1][5]. While ribosomal protein SA itself serves as a ribosomal protein as well as a multifunctional receptor involved in cell adhesion, migration, and various pathologies including cancer and prion diseases, the pseudogene RPSAP22 is an inactive genomic sequence that does not encode a functional protein. Most *RPSA* pseudogenes were formed by retropositional events and typically carry mutations (frameshifts, premature stop codons, missing start codons) that prevent them from coding for active proteins[1]. Some RPSA pseudogenes may produce non-coding RNA with potential regulatory functions, though there is no specific evidence for RPSAP22 itself. RPSAP22 is not a druggable or therapeutic target, as it does not produce a functional product or interface with drugs or disease processes.

Other names

RPSA_5_248RPSAP22

None. Drugs do not target RPSAP22 as a pseudogene.