Ribosomal protein SA pseudogene 28 (RPSAP28)

Ribosomal protein SA pseudogene 28 (RPSAP28) is classified as a processed pseudogene and does not encode a protein product[7][3]. It is one of many pseudogenes derived from retropositional events affecting the Ribosomal protein SA (RPSA) gene, which encodes the multi-functional 40S ribosomal protein SA—also known as the 37/67 kDa laminin receptor[5][3]. Pseudogenes such as RPSAP28 are typically non-functional genomic sequences that resemble known genes but lack coding potential due to mutations, deletions, or truncations[7]. They are not considered therapeutic or molecular targets, nor do they encode receptors, enzymes, or other functional molecules relevant for drug development or biomedical targeting. For molecular targeting, disease involvement, and drug action, information should be sought for the parent gene/protein (RPSA), not RPSAP28. The parent RPSA protein plays roles in ribosomal function, cell adhesion, infection, and cancer, but this does not apply to the pseudogene RPSAP28[5][3]. RPSAP28 is a pseudogene, not an active protein or receptor, and should not be considered a canonical molecular target for drug, diagnostic, or biomarker development[7][3][5]. If a molecular target is needed, focus should shift to Ribosomal protein SA (RPSA).

Other names

RPSAP28ribosomal protein SA pseudogene 28RPSA_4_242