Ribosomal protein SA pseudogene 31 (RPSAP31)

Ribosomal protein SA pseudogene 31 (RPSAP31) is a pseudogene related to the gene encoding ribosomal protein SA. Pseudogenes are sequences similar to functional genes but typically non-functional due to disabling mutations such as premature stop codons, frame shifts, or absence of promoter elements[7][9]. The authentic ribosomal protein SA gene (RPSA) encodes a protein that is part of the 40S ribosomal subunit and acts as a multifunctional protein, including roles as a receptor for laminin and involvement in processes such as translation, cell adhesion, infection, and cancer progression[3][5][7]. However, RPSAP31, as a pseudogene, does not produce a functional protein and is not regarded as a therapeutic target or receptor in drug development[7][9]. The family of RPSA pseudogenes is large, and most variants lack essential coding capacity for functional protein products[7][9]. Only very rare pseudogenes in this family potentially encode near-complete proteins, but RPSAP31 is not among those with documented functional capacity. For this reason, RPSAP31 should not be used as a synonym or substitute for the canonical RPSA gene or the protein it encodes. Note: The result does not correspond to a functional receptor or enzyme, so lists of function, disease associations, interacting drugs, and related mechanisms are not applicable. If you are seeking information on the biologically active “ribosomal protein SA” (also known as RPSA, 37/67 kDa laminin receptor), refer to the RPSA gene, not its pseudogenes[3][5][7].

Other names

RPSA_11_442RPSAP31