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Ribosomal protein SA pseudogene 36 (RPSAP36)
- Target
- RPSAP36
- Molecular classification
- Other (Pseudogene)
01
Overview
RPSAP36 (ribosomal protein SA pseudogene 36) is classified as a non-functional gene copy related to the ribosomal protein SA (RPSA) gene family. Pseudogenes are genetic sequences similar to functional genes but lack the ability to encode active proteins due to mutations such as frameshifts, premature stop codons, or missing regulatory elements. While some RPSA pseudogenes in other species have been studied for potential regulatory roles, there is no evidence that RPSAP36 in humans is functional or involved in any therapeutic pathway[5]. The canonical functional gene (RPSA) encodes a ribosomal protein, also acting as a cell surface receptor (laminin receptor), with roles in cancer and infectious disease[7]. However, pseudogenes like RPSAP36 are typically considered non-coding "genomic fossils" without therapeutic relevance.
- Other names
- RPSA_14_525RPSAP36
02
Mechanism of action
None. No mechanism of action is applicable as no drugs or therapies target this pseudogene.
03
Biological functions
Other (Pseudogenes by definition do not normally encode active proteins and thus lack classical protein functions[5].)
04
Disease associations
Other (There are no known disease associations with RPSAP36. Some RPSA pseudogenes may theoretically affect the expression or regulation of the functional RPSA gene, but specific roles for pseudogene 36 are undocumented[5].)
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