Ribosomal protein SA pseudogene 47 (RPSAP47)

Ribosomal protein SA pseudogene 47 (RPSAP47) is a processed pseudogene with high sequence similarity to the functional ribosomal protein SA (RPSA) gene, also known as the 37-kDa laminin receptor precursor or 67-kDa laminin receptor. This pseudogene was identified as part of large gene family surveys in bovine and ovine genomes. Like most pseudogenes, RPSAP47 does not produce a functional protein and is not considered a therapeutic target. Computational annotations and genomic analyses confirm its processed pseudogene status, with mutations such as premature stop codons and sequence deletions that prevent translation[3]. Further, pseudogenic loci like RPSAP47 may occasionally contribute to genome evolution, but this has not been demonstrated for RPSAP47 specifically. Pseudogenes can be misannotated or confused with functional genes in genomic databases, so care is required to distinguish them when searching for therapeutic or biological information[3].\n\nSummary of key issues:\n- "ribosomal protein SA pseudogene 47" is not a protein or receptor, but a non-functional pseudogene[3].\n- It should not be included in structured lists of therapeutic targets or druggable entities.

Other names

RPSAP47LOC786360: RPSA-like (GenBank, computational predictions)