Ribosomal protein SA pseudogene 5 (RPSAP5)

Ribosomal protein SA pseudogene 5 (*RPSAP5*) is a member of the processed pseudogene family related to the ribosomal protein SA gene (*RPSA*)[1][2]. Pseudogenes like *RPSAP5* typically arise from retrotransposition, resulting in non-functional copies that are usually not expressed as proteins[6][8]. There is no evidence that *RPSAP5* encodes a functional protein, acts as a receptor, or has a direct role in human disease or as a pharmacologic target[1][2][4]. Its parental gene, *RPSA*, is both a ribosomal protein and the laminin receptor, but *RPSAP5* itself does not share these properties[7]. Is there something wrong with this target? Yes. *RPSAP5* is a pseudogene, not a functional protein, enzyme, or receptor, and thus is not considered a valid biomedical target for drug discovery or therapeutic intervention[1][2][4]. Any reference treating it as a receptor or functional protein is not supported by experimental data. If you require information on the *functional* ribosomal protein SA or laminin receptor, you should refer to *RPSA* (canonical name: Ribosomal protein SA)[7].

Other names

LAMR1P5RPSA_22_1412Laminin receptor 1 pseudogene 5RPSAP5