Ribosomal protein SA pseudogene 55 (RPSAP55)

Ribosomal protein SA pseudogene 55 (RPSAP55) is a member of the RPSA gene family and is classified as a processed pseudogene, meaning it is a non-functional genomic sequence resembling the functional RPSA gene. RPSAP55 does not encode a protein and is not known to be expressed in a way that produces functional RNA or protein products. Its biological relevance is limited to possible regulatory functions, but none are described or experimentally validated for RPSAP55 specifically. It should not be confused with the functional Ribosomal protein SA (RPSA, also known as 37/67 kDa laminin receptor), which is involved in ribosomal function and acts as a cell surface receptor implicated in cancer and infectious diseases[3][5][7]. As a pseudogene, RPSAP55 has no known therapeutic, diagnostic, or mechanistic relevance, and is not considered a drug target. Pseudogenes like RPSAP55 do not encode functional proteins, and there is no evidence for a specific biological function for RPSAP55 itself[5]. No direct disease role for this specific pseudogene has been documented. The functional gene RPSA is implicated in cancer and prion disease, but not the pseudogene[5]. No evidence these aliases are used in the literature beyond gene annotations and database entries. RPSAP55 itself is a pseudogene, not a functional receptor, enzyme, or protein-coding gene; pseudogenes are generally not considered therapeutic targets[5][7]. There is also confusion risk since RPSA (ribosomal protein SA) is a known functional protein and target, but RPSAP55 is a related non-functional gene copy (pseudogene)[5][7]. If you are seeking a drug target or biomarker, consider Ribosomal protein SA (RPSA), not this pseudogene.

Other names

RPSA pseudogene 55RPSAP55RPSA_28_1433

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