Ribosomal protein SA pseudogene 56 (RPSAP56)

Ribosomal protein SA pseudogene 56 (RPSAP56) is one of multiple pseudogenes related to the functional *RPSA* gene, which encodes a ribosomal protein that also acts as a cell surface laminin receptor[3][5][1]. Pseudogenes like RPSAP56 typically arise from retrotransposition or gene duplication but accumulate mutations that prevent them from encoding a functional protein, and most are considered non-functional "genomic fossils." While some pseudogenes may exert regulatory roles at the RNA level, the specific function of RPSAP56 as an RNA or protein has not been established, and no data indicate that it serves as a disease biomarker, drug target, or protein-coding gene[5]. The only *RPSA* pseudogene in sheep shown to retain an open reading frame is RPSAP7, not RPSAP56[5]. The *RPSA* gene itself, not its pseudogenes, is involved in important cellular processes and disease, including cancer and interaction with pathogenic proteins[1][3]. The target is *not* a receptor, enzyme, transporter, or other therapeutic target. There is something incorrect with the query as a therapeutic target: RPSAP56 is a pseudogene, not a protein or receptor, and thus not druggable or functionally targeted. No roles or interactions relevant to drug development, biomarker discovery, or disease were found for RPSAP56. For anything beyond this (e.g., regulatory RNA roles), there is no supporting evidence for RPSAP56 specifically in humans or disease biology at this time[5].

Other names

RPSA_23_1496RPSAP56

Not applicable (no known function or drug interaction).